It confirmed 478,235 are first doses, with 33.3% of NI’s adult population having had at least their first jab.
The majority of adults are expected to be offered a vaccine by the summer.
Meanwhile, Health Minister Robin Swann has announced new arrangements for carers booking vaccinations.
Last week, the department opened up the programme to allow carers over the age of 18 to make a booking.
However, carers are now being asked to go through a Trust coordinator or wait to be called by their GP.
Officials have played down reports that the system was being abused as no proof of caring responsibilities had been required.
Earlier this week, Patricia Donnelly, who heads up NI’s vaccine programme, said the department was aware of a “couple of hundred cases” where people had tried to jump the queue.
Clare-Anne Magee, from Carers NI, said there are more than 300,000 carers in NI and hoped the process would continue to be smooth.
The “important point”, she said, was to encourage carers to come forward and be vaccinated.
Minister Swann said while a “significant number” of carers had taken up the offer, some “have not yet come forward or have not yet been able to book an appointment”.
Mrs Donnelly said reaching 500,000 vaccine doses meant a landmark number had been reached and the programme was ahead of schedule.
She said the scheme will push on as “quickly as supplies allow”, however, she added this has been “more of a stream than a river”.
To date, 25.6% of NI’s overall population has had at least a first dose, compared to 27.5% in England and Scotland, 28.1% in Wales and 4.4% in the Republic of Ireland.
What is Northern Ireland’s Covid-19 vaccine plan?
The supply of the Oxford-AstraZeneca vaccine to GPs is expected to increase from March, Ms Donnelly explained.
Health Minister Swann has described the vaccine rollout as a “large achievement”, which should not be underestimated.
The minister said there was evidence the vaccine rollout was having an impact on both “infection and transmissibility”.
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