Michael Dobbins, of Greenhaw Road in the city, appeared in court by videolink on the bill of indictment.
The 53-year-old was charged with six counts of rape on dates between January 1, 2013 and February 23, 2015.
He also faced two counts of sexual assault by penetration and one count of sexual assault.
Dobbins also faces one charge of sexual activity with a person with a mental disorder who would have been unable to consent on the same dates.
When the charged were put to him by the crown court clerk, Dobbins replied: “Definitely not guilty.”
No date for the trial, which is expected to last a fortnight, was set yet.
The case will be reviewed on Wednesday, July 7.
Dobbins was released on continuing bail until the review hearing next month.
In 2009, Dr Dobbins won the Headteacher of the Year in a Secondary School at the NI Teaching Awards held in Belfast.
Dr Dobbins became principal of Ardnashee School and College when Belmont House and Foyle View Schools merged in 2014.
Tags: