Devoted couple and peacemakers Pat and John Hume
Micheál Martin will join the President of the European Parliament, Roberta Metsola, in unveiling the bust later.
Mr Hume, a founding member of the SDLP, was one of the highest-profile politicians in Northern Ireland.
He died in Derry in 2020.
The former MEP was also a key architect of the Good Friday Agreement in 1998.
The sculpture was created by Irish artist Liz O’Kane and has been donated to the European Parliament by the Irish government.
A bust of former SDLP leader John Hume was unveiled in the garden of the Irish ambassador’s official residence in Washington in March this year
On Wednesday, the Taoiseach will address the European Parliament, reflecting on 50 years since Ireland decided to join the European Union.
