Jemma McGowan had been diagnosed with Stage 4 ovarian cancer in 2021.
Her heartbreaking story featured in a TV series with Stacey Dooley.
Jemma, from Co Tyrone, who was aged 29, was a mother of three.
News of her passing was announced early on Thursday.
An online notice said: “The death has taken place of Jemma McGowan, at her home, in the warm embrace of her beloved family. Formerly from Stewartstown. 16th December 1993 – 3rd August 2023.
“Beloved wife of Clive. Mother to Sadie, Louis and little Betty.
“Funeral arrangements to follow.
SDLP West Tyrone MLA Daniel McCrossan said: “This is very sad and a painful loss for all who know Jemma.
“Our thoughts and prayers are with her wee children, partner and wider family, friends at this very difficult time
West Tyrone MP Orfhlaith Begley posted: “RIP Jemma McGowan. Thinking of her husband and children at this difficult time.”
The type of ovarian cancer that Jemma battled is so rare it is believed to be the first case of its kind in the UK.
She was first diagnosed with ovarian cancer in 2016, while six weeks pregnant with her second child with her now-husband Clive, who she married in 2018.
The second diagnosis came after she discovered a lump in January 2021 while 35 weeks pregnant.
The following month, tests revealed she had advanced stage 4 incurable ovarian cancer which had spread to her lungs and pelvis.
In May 2021, she received the devastating news that there was nothing more doctors here could do.
Jemma documented her cancer journey on Instagram.
She also appeared on UKTV documentary series Stacey Dooley Sleeps Over, talking about her illness and family.
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