The men, aged 20, 20, 25 and 54 were charged with a number of drug related offences.
They are due to appear at Omagh Magistrates’ Court on Saturday, March 30, for a first remand hearing.
As is usual procedure all charges will be reviewed by the Public Prosecution Service.
Police said that during the proactive search a quantity of Class A and B Drugs along with a sum of cash was seized.
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