It comes after a number of attacks over the last week.
It will take place at the Guildhall at 6.15pm and focus on the need to end violence against women and girls.
Local SDLP councillor Catherine McDaid is one of those organising the rally, which will feature a range of speakers.
Councillor McDaid said: “Women across our city are living in fear after the events of the past week.
“We have seen four violent attacks on women who were just going about their lives, while walking home or out walking their dog.
“Nobody should be subjected to something like this and there will be a lasting impact on the victims of these horrific attacks.
“We cannot allow this to pass without a proper response. We are seeing self-defence classes for women reaching maximum capacity and discussions around how women stay safe are becoming an everyday reality.
“This isn’t an issue that has popped up this week, having to take safety precautions in normal situations is just part of life as a woman and points to a real sickness within our society.
“I think it’s really important that we come together as a city on Friday night to send a powerful message that this violence against women and girls must end.
“Everyone has their part to play in tackling this issue, we need a much improved response from the Executive, but we also need to see people taking responsibility for the actions and attitudes that have left women feeling unsafe in their own city.”
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